About Travoprost A synthetic prostaglandin F2a analogue, Ophthalmic Antiglaucoma. Mechanism of Action of Travoprost Travoprost is a prostaglandin F2-alpha analogue and it is a prostanoid selective FP receptor agonist which reduces the intraocular pressure (IOP) by increasing the outflow of aqueous humor mainly through increasing uveoscleral outflow. Indications for Travoprost 1.Open angle glaucoma Typical Dosage for Travoprost Adult:Apply one drop in the affected eyes once daily in the evening.