About Econazole Synthetic Imidazole derivative, Antifungal. Mechanism of Action of Econazole Econazole exerts its effects by altering cellular membrane and interfering with cellular enzymes.It is active against many fungi, dermatophytes and yeasts as well as some gram positive bacteria. Indications for Econazole 1.Cutaneous candidiasis 2.Tinea pedis 3.Tinea cruris 4.Tinea versicolor Typical Dosage for Econazole Cutaneous candidiasis: Gently rub sufficient quantity to the affected area 2 times daily. Tinea infection:Gently rub in to the affected area once daily.